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OncoCare

Cancer Topics

Articles
Malignant Fever–Discovering Cancer when a Patient has Fever (Part 1)
10/09/17    by: Dr Kevin Tay

Introduction

Many people would associate having a fever with infection. This is true most of the time. However, there are many situations where the body temperature is above normal and it is not due to infections. Some of these can be physiological causes (such as hot flashes), automimmune...

Hormone Positive Breast Cancer – What is Luminal B Breast Cancer?
30/08/17    by: Dr Peter Ang

There has been much publicity about using targeted therapy for cancer treatment. What is the first “targeted” therapy for breast cancer?

Well, actually, it should be hormonal or endocrine therapy. The development of treatments using medication that target the oestrogen (or estrogen) receptor...

Hormonal Therapy in Advanced Breast Cancer and Newer Agents to Overcome Resistance
03/08/17    by: Dr Tan Sing Huang , Dr Peter Ang

Because resistance to hormonal therapies can happen in up to a quarter of cases, newer therapeutic strategies have been developed to attempt to overcome this. There are several oral medications such as palbociclib, ribociclib or everolimus which when combined with pre-existing hormonal therapies...

What is HER2 Positive Breast Cancer?
01/07/17    by: Dr Peter Ang

Breast cancer is the most frequently diagnosed cancer worldwide and the leading cause of cancer death in women. In Singapore, breast cancer is the most commonly diagnosed cancer for more than 40 years and it is the leading cause of death in cancers affecting women. There are more than 7000 new...

Harnessing the Immune System to Fight Cancer Part 2 -Immunotherapy
14/06/17    by: Dr Peter Ang , Dr Thomas Soh

Introduction

As discussed in Part 1, immune surveillance is important in preventing cancer. It was noted more than 100 years ago, that cancers had immune cells around them known as lymphocytes or tumour infiltrating lymphocytes (TILs).

In the simplest description, the process of developing...

Harnessing the Immune System to Fight Cancer - Part 1
19/04/17    by: Dr Peter Ang

Introduction

Many people would be familiar with therapies to treat cancer including chemotherapy, radiation, surgery and even targeted therapy. There has been excitement and news of boosting or harnessing the immune system as treatment in some cancers. Immunotherapy is a type of treatment that...

Colon Cancer Presenting as Blood in the Stools
06/04/17    by: Dr Peter Ang , Dr Benjamin Chuah

Seeing blood in the stools is distressing and frightening to a lot of people. The uncertainty of where it comes from, and whether there is an underlying serious illness such as cancer adds to the fear. This concern is magnified when there is a large quantity of blood, when it is fresh red and...

Ten Facts about Triple Negative Breast Cancer (TNBC)
07/03/17    by: Dr Peter Ang

In Singapore, breast cancer is the most commonly diagnosed cancer for more than 40 years and it is the leading cause of death in cancers affecting women. There are more than 7000 new cases a year (from 2006-2010) and it has been a rising incidence trend. The incidence rises sharply after 30...

Carcinoma, Sarcoma, Myeloma, Lymphoma and Leukemia - What Cancer is That?
02/02/17    by: Dr Peter Ang , Dr Kevin Tay

At OncoCare Cancer Centre, we sometimes see patients who have received a report and are confused by the cancer names or terminology. Some patients have been informed by their treating doctor or surgeon that they have a lump removed and that it is a tumor (or tumour). They next receive a report...

What are GISTs?
16/01/17    by: Dr Thomas Soh

Introduction

GISTs, or gastrointestinal stromal tumours, are uncommon tumours that originate from the digestive system. However, they are different from the more frequent types of digestive tract cancers or adenocarcinomas, as they are specifically derived from unique cells called the...