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Cancer Topics

Cancer risk and BRCA genes – the future can sometimes be known
21/12/17    by: Dr Peter Ang

At OncoCare Cancer Centre, Singapore, we see many patients with their families who come to provide support for the patient and often are involved in the discussion of care for the patient. Frequently, a relative may ask (or just think in their mind) what the implication of the relatives’...

Colon Cancer
28/11/17    by: Dr Peter Ang , Dr Wong Nan Soon

As part of the digestive tract, the large intestine consists of the caecum (or cecum), ascending colon, transverse colon, descending colon, sigmoid colon and the rectum. Colorectal cancer refers to a cancer arising from these parts of the large intestine. The anatomy of the large intestine is...

The Tumour has Spread to the Brain…
12/11/17    by: Dr Peter Ang , Dr Benjamin Chuah

What is the most common brain tumour in adults? It is actually metastatic brain tumour; estimated to be about 200,000 cases in the United States annually. The term for cancer spreading to the brain tissue is brain metastasis or brain secondaries. It is a serious condition presenting as a major...

Preventive surgery for ovary cancer in BRCA mutation carriers
31/10/17    by: Dr Peter Ang

Ms Angelina Jolie has spoken about her decision to have preventive surgery for ovary cancer in Mar 2015 in the New York Times. She is known to carry a hereditary mutation in the BRCA1 gene, which increased her risk for ovarian cancer and breast cancer. In addition, the type of breast cancer...

Back Pain : When Cancer is Bone Deep
03/10/17    by: Dr Kevin Tay

Many people would have experienced back pain at some point in our life, and it is a common reason for work-related absence or a visit to the doctor’s. Although back pain may be painful and uncomfortable, it is not usually serious, but in some instances, it may portend a more ominous cause.

Malignant Fever–Discovering Cancer when a Patient has Fever (Part 2)
24/09/17    by: Dr Kevin Tay


In patients with malignant fever, the onset of fever may sometimes precede other clinical manifestations and may be the first clue that patient has an underlying cancer.  There is usually no specific fever pattern seen in patients with...

Malignant Fever–Discovering Cancer when a Patient has Fever (Part 1)
10/09/17    by: Dr Kevin Tay


Many people would associate having a fever with infection. This is true most of the time. However, there are many situations where the body temperature is above normal and it is not due to infections. Some of these can be physiological causes (such as hot flashes), automimmune...

Hormone Positive Breast Cancer – What is Luminal B Breast Cancer?
30/08/17    by: Dr Peter Ang

There has been much publicity about using targeted therapy for cancer treatment. What is the first “targeted” therapy for breast cancer?

Well, actually, it should be hormonal or endocrine therapy. The development of treatments using medication that target the oestrogen (or estrogen) receptor...

Hormonal Therapy in Advanced Breast Cancer and Newer Agents to Overcome Resistance
03/08/17    by: Dr Tan Sing Huang , Dr Peter Ang

Because resistance to hormonal therapies can happen in up to a quarter of cases, newer therapeutic strategies have been developed to attempt to overcome this. There are several oral medications such as palbociclib, ribociclib or everolimus which when combined with pre-existing hormonal therapies...

What is HER2 Positive Breast Cancer?
01/07/17    by: Dr Peter Ang

Breast cancer is the most frequently diagnosed cancer worldwide and the leading cause of cancer death in women. In Singapore, breast cancer is the most commonly diagnosed cancer for more than 40 years and it is the leading cause of death in cancers affecting women. There are more than 7000 new...