Home » Specialists » Dr Valerie Yang Shiwen
BSc (First Class Honors), MBBChir (Cambridge), PhD (Cambridge), MRCP (UK), FAMS (Medical Oncology, Clinician Scientists)
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Dr. Valerie Yang is a Senior Medical Oncologist at OncoCare Cancer Centre, dedicated to providing personalized care to each patient. With over 15 years of clinical experience and translating cutting-edge approaches to clinical care, she focuses on managing complex cancers, including rare cancers, sarcomas, skin cancers, melanomas, lymphomas and general oncology.
Dr. Yang is also jointly appointed as Group Leader of the Translational Precision Oncology Laboratory at the Institute of Molecular and Cell Biology (IMCB), Adjunct Principal Investigator at the Bioinformatics Institute, A*STAR, Adjunct Assistant Professor at Duke-NUS Medical School and Visiting Consultant at the National Cancer Centre Singapore, where her translational research bridges real-world data, advanced genomic and spatial technologies, patient-derived models and functional precision oncology to bring effective treatments to patients.
Dr Yang has presently authored over 60 publications and book chapters. These were presented at multiple global conferences including the American Society of Clinical Oncology (ASCO), European Society of Medical Oncology (ESMO), American Association for Cancer Research (AACR), the Connective Tissue Oncology Society (CTOS) and others.
A graduate of the MB/PhD programme at the University of Cambridge, Dr. Yang has won several awards, including the First Prize in open competition across Cambridge University’s PhD candidates in Biological Sciences and the Sylvia Lawler Prize from the Royal Society of Medicine. She is also a member of a three-person international scholar selection panel for the Gates Cambridge Trust for Biological Sciences. She is a National Science Scholar under Singapore’s A*STAR scholarship program. Her clinical training in Internal Medicine and Medical Oncology was completed at leading institutions in Singapore, including the National University Hospital (NUH) and the National Cancer Centre Singapore (NCCS).
Dr. Yang has received numerous accolades, including the prestigious National Medical Research Council (NMRC) Transition Award as an Associate Consultant and a 25-million-dollar Open Fund Large Collaborative Grant as Theme Principal Investigator. Internationally, she holds key roles in global networks for rare cancers and sarcomas, representing Singapore in clinical trials and research collaborations both academic and with industry. She also co-chairs the biennial Singapore Sarcoma & Skin Cancers Symposium. She has also taught at NUS, Duke-NUS Medical School and has mentored over 30 students ranging from science and medical students to Masters and PhD students.
Fluent in English, Mandarin, and Bahasa Melayu/Indonesia, Dr. Yang ensures that patients from diverse backgrounds feel heard and supported. She is also a strong advocate for several patient support groups. She has received named referrals for rare cancers and sarcomas from all over the world, including Indonesia, Vietnam, Thailand, Cambodia, Myanmar, Japan, Australia, the United Arab Emirates, United Kingdom, Germany, France, Poland, South Africa and Inner Mongolia.
Dr Yang has been featured in the news for her work in personalized treatments for rare cancers and patient support: https://www.zaobao.com.sg/news/singapore/story20241007-4658743
Dr Yang is sought-after in the field of rare cancers and translational oncology. A selection of her invited clinical presentations include:
She has also been featured in medical education events, webinars, and grand rounds for her insights into oncology drug approvals and clinical trial innovation.
Dr Yang has led numerous clinically impactful studies as senior and corresponding author, including:
These articles have shaped ongoing global conversations around therapy selection, biomarker utility, and patient-centered care in rare and aggressive cancers.
Dr Yang has published over 60 peer-reviewed articles in prestigious and high-impact journals. Her work has been cited and is referenced in guideline-setting discussions and global oncology conferences.
Dr Yang is Principal Investigator of several clinical trials and has designed clinical trials in rare cancers to translate specific findings from her laboratory to patients. She continues to lead efforts integrating translational science with precision clinical trial approaches for difficult-to-treat cancers.
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